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Question
Biology
Posted 10 months ago
how do we use RNA homopolymers to decipher what genes code for
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Answer from Sia
Posted 10 months ago
Answer
RNA homopolymers are used to determine the specificity of RNA codons for amino acids.
Solution
a
Synthesizing RNA Homopolymers: RNA homopolymers are synthesized with a known sequence of a single type of nucleotide, such as poly-U (uracil), poly-A (adenine), poly-C (cytosine), or poly-G (guanine)
b
In Vitro Protein Synthesis: These homopolymers are then used in a cell-free protein synthesis system, where they serve as artificial mRNA templates
c
Determining Codon Specificity: By observing which amino acids are incorporated into the synthesized polypeptides, scientists can infer the codons that correspond to specific amino acids. For example, if poly-U is used and the polypeptide produced is polyphenylalanine, it indicates that UUU codes for phenylalanine
Key Concept
RNA homopolymers help decipher the genetic code by indicating which codons correspond to specific amino acids.
Explanation
By using RNA homopolymers in a cell-free system, scientists can determine the amino acids specified by particular codons, thus helping to decode the genetic language.

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