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Question
Biology
Posted 10 months ago
how do bacterial cells respond to thymidine dimers caused by UV radiation
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Answer from Sia
Posted 10 months ago
Answer
Bacterial cells respond to thymidine dimers caused by UV radiation primarily through two repair mechanisms: photoreactivation and nucleotide excision repair (NER).
Solution
a
Photoreactivation: This process directly reverses the damage caused by UV radiation
b
Nucleotide excision repair (NER): This is a more complex process that removes the damaged section of DNA and replaces it with the correct nucleotides
Key Concept
DNA Repair Mechanisms in Bacteria
Explanation
When bacterial cells are exposed to UV radiation, thymidine dimers form between adjacent thymine bases, disrupting normal base pairing and DNA replication. Bacteria utilize specific repair mechanisms to correct these lesions and maintain genomic integrity. Photoreactivation involves a light-activated enzyme called photolyase that directly repairs the dimers. Nucleotide excision repair is a more general mechanism that excises the damaged DNA segment and fills in the gap with newly synthesized DNA using the undamaged strand as a template.

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