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Question
Biology
Posted 10 months ago
Which of genetic testing platforms would best identify a 10 megabase chromosomal translocation?
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Answer from Sia
Posted 10 months ago
Answer
Chromosomal Microarray (CMA)
Solution
a
Chromosomal Microarray (CMA) : is designed to detect large chromosomal imbalances, including translocations, and is capable of identifying changes as small as 1 megabase (Mb) or even smaller in some cases. A 10 megabase translocation would likely be detected by this method
Key Concept
Chromosomal Microarray's Sensitivity
Explanation
CMA is sensitive enough to detect large chromosomal rearrangements such as a 10 megabase translocation, making it the best choice for identifying such genetic changes.
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