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Question
Biology
Posted 9 months ago
What is the role of ADP in kinesin transport?
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Answer from Sia
Posted 9 months ago
Answer
ADP is involved in the energy transfer that powers kinesin movement along microtubules.
Solution
a
ADP release: Kinesin binds to microtubules and hydrolyzes ATP to ADP, which provides energy for conformational changes necessary for movement
b
Conformational change: The release of ADP from kinesin leads to a change in the shape of the kinesin molecule, which results in the "stepping" motion along the microtubule
Key Concept
ADP and energy transfer
Explanation
ADP is the product of ATP hydrolysis, which occurs when kinesin interacts with microtubules. The energy released during this process is used to induce conformational changes in kinesin that propel it along the microtubule, transporting various cellular cargoes.
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