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Question
Biology
Posted 10 months ago
What is the function of the autophagosome in the process of autophagy?
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Answer from Sia
Posted 10 months ago
Answer
The autophagosome is a double-membraned vesicle that plays a crucial role in autophagy by sequestering cytoplasmic material, including damaged organelles and proteins, for degradation.
Solution
a
Sequestration of cytoplasmic material: The autophagosome engulfs portions of the cytoplasm, damaged organelles, and misfolded proteins
b
Fusion with lysosomes: After formation, the autophagosome fuses with a lysosome to form an autolysosome, where the sequestered material is degraded by lysosomal enzymes
c
Recycling of cellular components: The breakdown products are then recycled back into the cytosol for reuse, aiding in cellular maintenance and survival
Key Concept
Autophagosome formation and function in autophagy
Explanation
The autophagosome is essential for capturing and delivering cellular components to lysosomes for degradation and recycling, thus maintaining cellular homeostasis.
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