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Biology
Posted 10 months ago

The reactions from fructose-6 - phosphate to fructose-1, 6 - bisphosphate in glycolysis and back again nn gluconeogenesis are said to be reciprocally regulated.
a. What does that mean? Use the terms reverse reaction and reverse pathway in your answer.
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Answer from Sia
Posted 10 months ago
Answer
Reciprocal regulation in the context of glycolysis and gluconeogenesis means that the reaction converting fructose-6-phosphate to fructose-1,6-bisphosphate in glycolysis, and the reverse reaction in gluconeogenesis, are regulated in opposite manners.
Solution
a
Reciprocal regulation : This term refers to a biochemical mechanism where the forward reaction and the reverse reaction are regulated in such a way that when one is active, the other is suppressed
b
Reverse reaction and reverse pathway : In the context of glycolysis and gluconeogenesis, the reverse reaction refers to the conversion of fructose-1,6-bisphosphate back to fructose-6-phosphate, which is part of the reverse pathway of gluconeogenesis, as opposed to the forward pathway of glycolysis
Key Concept
Reciprocal regulation of metabolic pathways
Explanation
Reciprocal regulation ensures that energy is not wasted by having both the forward and reverse pathways active at the same time, which would lead to a futile cycle of synthesis and breakdown of the same molecules.

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