Proline disrupts an a-helix structure because:

Select one
a. bulky side chains
b. it has a secondary amino group which is not geometrically compatible with the righthanded spiral of the a-helix.
C. branch at the $\beta$-carbon
d. forming ionic bonds

Question

Proline disrupts an a-helix structure because:

Select one
a. bulky side chains
b. it has a secondary amino group which is not geometrically compatible with the righthanded spiral of the a-helix.
C. branch at the $\beta$-carbon
d. forming ionic bonds

Accepted Answer

***B*** ∻Key Concept∻ ⚹Proline and alpha-helix disruption⚹ ∻Explanation∻ ⚹Proline has a unique ring structure that includes a secondary amino group, which is not geometrically compatible with the right-handed spiral of the alpha-helix. This causes a kink or disruption in the helix.⚹◊How does the presence of a secondary amino group in proline affect the structure of an α-helix in proteins?⍭ Generate me a similar question◊

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