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Sia

青州's Question
Chemistry
Posted 10 months ago

If 1.0 g1.0 \mathrm{~g} of hyoscyamine was dissolved in 200 mL200 \mathrm{~mL} of water, how much hyoscyamine would be left remaining in the aqueous solution after extracting once with 100 mL100 \mathrm{~mL} of diethyl ether? How much hyoscyamine would be left remaining in the aqueous solution if two extractions with 50 mL50 \mathrm{~mL} of diethyl ether were performed instead? Which extraction method would be more efficient at removing hyoscyamine from the aqueous solution? The partition coefficient, K\mathrm{K}, of hyoscyamine in this system is 4.07 .
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Answer from Sia
Posted 10 months ago
Solution
1
Calculate the amount of hyoscyamine in diethyl ether after the first extraction: Use the partition coefficient KK to determine the ratio of concentrations between diethyl ether and water. The partition coefficient KK is defined as K=[hyoscyamine]ether[hyoscyamine]waterK = \frac{[hyoscyamine]_{ether}}{[hyoscyamine]_{water}}
2
Determine the initial concentration of hyoscyamine in water: The initial concentration CwaterC_{water} is calculated by dividing the mass of hyoscyamine by the volume of water, Cwater=1.0 g200 mLC_{water} = \frac{1.0 \text{ g}}{200 \text{ mL}}
3
Apply the partition coefficient to find the final concentrations: After the first extraction, the concentration in diethyl ether CetherC_{ether} can be found using Cether=KCwaterC_{ether} = K \cdot C_{water}. The amount of hyoscyamine in 100 mL of diethyl ether is then Cether×100 mLC_{ether} \times 100 \text{ mL}
4
Calculate the remaining amount of hyoscyamine in water after the first extraction: Subtract the amount extracted by diethyl ether from the initial amount to find the remaining amount in water
5
Repeat the calculation for two extractions with 50 mL of diethyl ether: For each extraction, recalculate the concentration in water and use the partition coefficient to find the new concentration in diethyl ether. Then, calculate the remaining amount in water after each extraction
6
Compare the efficiency of the two extraction methods: The method that results in the least amount of hyoscyamine remaining in the aqueous solution is more efficient
1 Answer
[Insert final answer for the first extraction here]
2 Answer
[Insert final answer for the two extractions here]
3 Answer
[Insert which method is more efficient here]
Key Concept
The partition coefficient is a measure of a compound's distribution between two immiscible solvents and is key to solving extraction problems.
Explanation
The partition coefficient allows us to calculate the concentration of a solute in two phases at equilibrium, which is essential for determining the amount of solute remaining after extraction.

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