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Question
Biology
Posted 10 months ago
How does high fructose corn syrup differ in its metabolism from glucose and why does it contribute to obesity in children and adults?
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Answer from Sia
Posted 10 months ago
Answer
High fructose corn syrup (HFCS) is metabolized differently than glucose, which may contribute to obesity in children and adults.
Solution
a
Metabolic Pathway Differences : HFCS is composed of fructose and glucose. Fructose is metabolized primarily in the liver, whereas glucose is metabolized by all cells in the body
b
Lipogenesis Promotion : Fructose metabolism in the liver can lead to increased lipogenesis (fat production), which is not as significant when glucose is metabolized
c
Leptin Resistance : Fructose consumption may lead to leptin resistance, which impairs satiety signals and can lead to overeating
d
Insulin Resistance : High intake of fructose can contribute to insulin resistance, a precursor to obesity and type 2 diabetes
Key Concept
Metabolic differences between HFCS and glucose
Explanation
HFCS is metabolized mainly in the liver, leading to increased fat production and potential leptin and insulin resistance, which can contribute to obesity.

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