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Question
Biology
Posted 10 months ago
During prophase of mitosis, what role do the microtubule - associated proteins (MAPs) and depolymerisation factors play in the formation and function of the mitotic spindle?
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Answer from Sia
Posted 10 months ago
Answer
During prophase of mitosis, MAPs stabilize and promote the assembly of microtubules, while depolymerization factors regulate microtubule dynamics necessary for the formation of the mitotic spindle.
Solution
a
Role of MAPs: Microtubule-associated proteins (MAPs) stabilize and promote the polymerization of microtubules, which are essential for the formation of the mitotic spindle
b
Role of depolymerization factors: Depolymerization factors are involved in the regulation of microtubule dynamics by promoting the disassembly of microtubules at their ends. This activity is crucial for the proper adjustment and maintenance of spindle length and tension during mitosis
Key Concept
Microtubule dynamics in mitosis
Explanation
MAPs and depolymerization factors work in concert to regulate the stability and length of microtubules, ensuring the proper formation and function of the mitotic spindle during prophase.
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