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Biology
Posted 9 months ago

Differentiate two alternatives to glycolysis - pentose phosphate and Entner - Doudoroff pathways.
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Answer from Sia
Posted 9 months ago
Answer
The pentose phosphate pathway and the Entner-Doudoroff pathway are two alternative metabolic pathways to glycolysis.
Solution
a
Pentose Phosphate Pathway: This pathway primarily serves to generate NADPH and ribose-5-phosphate. NADPH is crucial for biosynthetic reactions, while ribose-5-phosphate is a precursor for nucleotide synthesis. The pathway can be divided into two phases: the oxidative phase, which produces NADPH, and the non-oxidative phase, which synthesizes ribose-5-phosphate and other sugars
b
Entner-Doudoroff Pathway: This pathway is an alternative to glycolysis found in some bacteria. It converts glucose to pyruvate and glyceraldehyde-3-phosphate, yielding ATP and NADPH. Unlike glycolysis, which produces two molecules of ATP per glucose, the Entner-Doudoroff pathway produces only one molecule of ATP per glucose
Key Concept
Pentose Phosphate Pathway and Entner-Doudoroff Pathway
Explanation
The pentose phosphate pathway generates NADPH and ribose-5-phosphate, essential for biosynthesis and nucleotide synthesis, respectively. The Entner-Doudoroff pathway, found in some bacteria, converts glucose to pyruvate and glyceraldehyde-3-phosphate, yielding ATP and NADPH, but with a lower ATP yield compared to glycolysis.

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