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Question
Biology
Posted 9 months ago

Comparing the LD50 and ID50 values for wild - type and NeMut1 strain, what conclusion can be drawn regarding the virulence of NeMut1 compared to wild - type strain in this model of infection?
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Answer from Sia
Posted 9 months ago
Answer
The NeMut1 strain is less virulent compared to the wild-type strain.
Solution
a
LD50 (Lethal Dose 50): This is the dose of a pathogen required to kill 50% of the test population. A higher LD50 value indicates lower virulence because it takes a larger amount of the pathogen to cause death
b
ID50 (Infectious Dose 50): This is the dose of a pathogen required to infect 50% of the test population. A higher ID50 value indicates lower virulence because it takes a larger amount of the pathogen to cause infection
c
Comparing LD50 and ID50 values: If the NeMut1 strain has higher LD50 and ID50 values compared to the wild-type strain, it means that NeMut1 is less virulent. This is because it requires a higher dose to cause the same level of infection or death as the wild-type strain
Key Concept
Virulence comparison using LD50 and ID50 values
Explanation
The virulence of a pathogen can be assessed by comparing the LD50 and ID50 values. Higher values indicate lower virulence, meaning the pathogen is less effective at causing disease or death.

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