(4.29) In Drosophila, the autosomal recessive brown eye color mutation displays interactions with both the $\mathrm{X}$-linked recessive vermilion mutation and the autosomal recessive scarlet mutation. Flies homozygous for brown and simultaneously hemizygous or homozygous for vermilion have white eyes. Flies simultaneously homozygous for both the brown and scarlet mutations also have white eyes. Predict the $F_{1}$ and $F_{2}$ progeny of crossing the follow true-breeding parents:
a. vermilion females $ imes$ brown males
b. brown females $ imes$ vermilion males
c. scarlet females $ imes$ brown males
d. brown females $ imes$ scarlet males

Question

(4.29) In Drosophila, the autosomal recessive brown eye color mutation displays interactions with both the $\mathrm{X}$-linked recessive vermilion mutation and the autosomal recessive scarlet mutation. Flies homozygous for brown and simultaneously hemizygous or homozygous for vermilion have white eyes. Flies simultaneously homozygous for both the brown and scarlet mutations also have white eyes. Predict the $F_{1}$ and $F_{2}$ progeny of crossing the follow true-breeding parents:
a. vermilion females $	imes$ brown males
b. brown females $	imes$ vermilion males
c. scarlet females $	imes$ brown males
d. brown females $	imes$ scarlet males

Accepted Answer

Sure, let's analyze the given Drosophila genetics problem and predict the $F_1$ and $F_2$ progeny for each cross. ### a. vermilion females $×$ brown males ***D*** ∻Key Concept∻ ⚹Genetic interaction between vermilion and brown mutations⚹ ∻Explanation∻ ⚹Vermilion is an X-linked recessive mutation, and brown is an autosomal recessive mutation. The $F_1$ progeny will be heterozygous for both traits, and the $F_2$ progeny will show a 1:1:1:1 ratio of phenotypes due to independent assortment.⚹ ### b. brown females $×$ vermilion males ***D*** ∻Key Concept∻ ⚹Genetic interaction between brown and vermilion mutations⚹ ∻Explanation∻ ⚹Brown is an autosomal recessive mutation, and vermilion is an X-linked recessive mutation. The $F_1$ progeny will be heterozygous for both traits, and the $F_2$ progeny will show a 1:1:1:1 ratio of phenotypes due to independent assortment.⚹ ### c. scarlet females $×$ brown males ***D*** ∻Key Concept∻ ⚹Genetic interaction between scarlet and brown mutations⚹ ∻Explanation∻ ⚹Scarlet and brown are both autosomal recessive mutations. The $F_1$ progeny will be heterozygous for both traits, and the $F_2$ progeny will show a 9:3:3:1 ratio of phenotypes due to independent assortment.⚹ ### d. brown females $×$ scarlet males ***D*** ∻Key Concept∻ ⚹Genetic interaction between brown and scarlet mutations⚹ ∻Explanation∻ ⚹Brown and scarlet are both autosomal recessive mutations. The $F_1$ progeny will be heterozygous for both traits, and the $F_2$ progeny will show a 9:3:3:1 ratio of phenotypes due to independent assortment.⚹◊What is the expected phenotype of the $F_{1}$ and $F_{2}$ progeny when vermilion females are crossed with brown males in Drosophila?⍭ Generate me a similar question◊

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